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I just applied FRONTLINE, but I still see active fleas. Why?   Date: Saturday 27 November, 2004
FAQ Summary:
Fipronil, an active ingredient of FRONTLINE, works by blocking stabilizing ions in the neurons of invertebrates like fleas. Without the stabilizing ions, the fleas die from hyperstimulation. This means that the fleas may become slightly more active just before they die. However, you should rest assured that this is a sign that FRONTLINE is working.

FAQ Content:
Fipronil, an active ingredient of FRONTLINE, works by blocking stabilizing ions in the neurons of invertebrates like fleas. Without the stabilizing ions, the fleas die from hyperstimulation. This means that the fleas may become slightly more active just before they die. However, you should rest assured that this is a sign that FRONTLINE is working.

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